Do agglomerated corks pose health risk?

Oct 03, 2004 1 Replies
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Medline Abstract



GB Jiang, JY Liu, and QF Zhou Search for the contamination source of butyltin compounds in wine: agglomerated cork stoppers. Environ Sci Technol, August 15, 2004; 38(16): 4349-52.



Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China. snipped-for-privacy@mail.rcees.ac.cn



A possible butyltin contamination source in wine was studied in this paper. Agglomerated cork stoppers, which were produced in Portugal, Spain, and Italy, used in wine bottles were examined. The domestic cork products, cork granules, and mucus used for cork products were also analyzed. The levels of mono- and dibutyltin compounds in corks were found in the range from


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908938&dopt«stract

Environ Res. 2002 Feb;88(2):129-33. Butyltin compounds in human liver.

Nielsen JB, Strand J.

Institute of Public Health, University of Southern Denmark, Odense C, DK-5000, Denmark.

Intake of marine food is the main source of butyltin exposure in humans. Health effects following exposure to butyltin compounds are usually in the immune system, but endocrine effects of butyltin from a variety of marine species have been documented. The information on human exposure to butyltin compounds and hepatic deposition is limited. The present study include 18 consecutively sampled human livers analyzed for butyltin compounds. Dibutyltin (DBT) concentrations varied between 0.8 and 28.3 ng/g with a mean concentration of 9.0 ng/g. Significantly lower concentrations of monobutyltin (MBT) were observed, ranging from 0.3 to 4.7 ng/g with a mean value of 1.6 ng/g. Age and DBT/MBT ratio were significantly associated. We suggest that younger men have more recent exposures or have a lower capacity to debutylate DBT than older men and would therefore potentially be more susceptible to butyltin toxicity. Given the interperson variability observed in our limited group of men, we cannot exclude that thresholds for either immunotoxicity or effects on the endocrine system may occur due to exposure to butyltin compounds alone or in combination with other environmental toxicants with similar target organs.

PMID: 11908938 [PubMed - indexed for MEDLINE]

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