...In times when you don't want them (which is 99.9% of the time for me, as I am basically a non-drug/alcohol/tobacco/caffeine user - i.e., I only eat food and beverages with no mind-altering properties) that is.
Basically I am really annoyed how often I have to _specifically check_ what foods and beverages I consume to make sure they don't contain any IRRITATING compounds. For example, today I had a couple candy bars (chocolate containing) and I had trouble getting relaxed in the evening, thanks to the irritants (caffeine, etc) in these candy bars. I'm someone who has dealt with mental health issues in the past (in my teens and early 20's) and I just recently (4 months ago) quit cannabis, caffeine, and psychiatric medications (Risperdal and Effexor) all cold turkey, all at once.
I now try my best every day to live a healthy lifestyle and exercise when I can on my days off. What really pisses me off is how our society has such a relaxed attitude towards caffeine and its related alkaloids, when in fact they are probably one of the biggest causes of heart disease - which is in fact the #1 killer of human beings in the United States.
I have come to the conclusion that the U.S. Government only legalizes the consumables which are the most deadly, so essentially they are mass murderers. Alcohol is a poison, caffeine is toxic, and nicotine is a poison. On the other hand, everything that is _illegal_ has some or many medicinal uses to keep people healthy, whether that be spiritually or physically - cannabis is the most healthy plant known to mankind, coca leaves are one of the most nutricious of plants, and opium poppies have thousands of medicinal uses. And they are all illegal for citizens to possess or consume. Ironic, isn't it...