Might be a daft question but can wine be made with a low calorie sugar
> substitute, I'm getting fat
I think you were right the first time -- it's a daft question.
Firstly, yeast need sugar to ferment into alcohol. If you start with something other than sugar, the yeast won't be able to digest it, and you won't get wine. Without the alcohol content to act as a preservative, the stuff you started with would probably spoil rather quickly.
Secondly, it is possible to use a sugar substitute to sweeten a wine, after the real sugars have been fermented. I believe most of the readily-available sugar substitutes have problems of one sort or another in this regard, but have not researched it. There have been discussions in this newsgroup over the past year or so about the prospects for one or another new sweetener.
For what I drink, the calories are in the alcohol, not in the residual sugar (if any), so it wouldn't make any meaningful impact on my caloric intake. Unless you drink a whole lot of very sweet wine, I would guess that would apply to you, too.
Try water instead; it's bound to be better for you. Or cut back on something else. Sorry --
Doug